Research at Fertility Center of Las Vegas Finds Innovative Breakthrough for Increasing IVF Pregnancy Rates
(sz) Research at Fertility Center of Las Vegas Finds Innovative Breakthrough for Increasing IVF Pregnancy Rates – Getting the Embryo “in sync” With the Endometrium
The January 2008 issue of the nations preeminent journal of reproductive medicine, Fertility & Sterility, featured a research article by Dr. Bruce Shapiro and Dr. Said Daneshmand of the Fertility Center of Las Vegas. That article, titled “Contrasting patterns in in vitro fertilization pregnancy rates among fresh autologous, fresh oocyte donor, and cryopreserved cycles using day 5 or day 6 blastocysts may reflect differences in embryo-endometrium synchrony”, points out how pregnancy rates in IVF cycles can be strongly influenced by endometrial receptivity.
Specifically, the research finds that many slowly developing embryos fail to implant because they tend to miss the endometrium’s receptive phase because the endometrium is advanced by ovarian stimulation. Heretofore, it was commonly assumed that slow embryos were less viable. Now it seems they are only out of synchrony with the endometrium.
The salient point of this research was to show that the reduced pregnancy rate with slow embryos, specifically day 6 blastocysts, only appeared in fresh non-donor cycles. The effect disappeared in cycles using thawed embryos and in cycles of egg donation. Interestingly, it only appeared in cycles where the woman receiving the transferred embryos had just undergone ovarian stimulation. more…
From: »NewsReleaseWire« (press release)