Presented at ASRM:
Sperm Abnormalities Correlate With Age
(wz) Men with sperm abnormalities, such as DNA-fragmented spermatozoa, are usually given a chance to father a child through intracytoplasmic sperm injection (ICSI), instead of the regular in vitro fertilization (IVF). Either ICSI or IVF technique is recommended based on standard sperm characteristics, yet they are not good enough markers, judging from the rates of success of the treatment.
A team of German researchers approached this issue from the point of view of sperm genome quality, and are drawing the line between good and bad sperm at age 35, according to a study reported here at the 63rd Annual Meeting of the American Society for Reproductive Medicine (ASRM).
The researchers triggered the DNA fragmentation, or rather the amount of sperm with fragmented DNA and attempted to correlate it with the patient’s age, explained Thomas Winkle, Doctoral Researcher, Institute for Reproductive Medicine and Genetics, ReproGen-Ulm, Ulm, Germany, in an interview on October 16.
Semen samples were collected from all patients accrued in this study at the IVF-Zentrum, Ulm, Germany. Patients were between 24 and 47 years old. more…
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