Leukaemia and Down’s Syndrome Linked in Infants Whose Mothers Underwent Fertility Treatments: Presented at AACR
(sz) LOS ANGELES, CA — It is well known that a woman’s age increases her risk of her having a child with Down’s syndrome. Now, a study presented here at the American Association for Cancer Research (AACR) annual meeting suggests that children with Down’s syndrome have a greater risk of developing leukaemia if their mother underwent any kind of fertility treatment.
In this study, the risk of leukaemia, specifically acute myeloid leukaemia (AML), was 2.5 times greater (odd ratio = 2.47, 95% CI, 1.02 - 5.97) among children with Down’s syndrome whose mothers had tried to conceive for more than a year, according to Susan Puumala, PhD candidate in childhood cancers, University of Minnesota, Minneapolis, Minnesota, United States.
Among mothers who had undergone surgical fertility treatments (including in vitro fertilisation) the odds ratio increased to 2.78, the researcher said in an interview. more…
From: »Doctor’s Guide«